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JG26

CAT: 1410-M34294-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:1410-M34294-03Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body.
CAS Number
1464910-32-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
594.27
Molecular Formula
C19H22Br2N4O6S
Notes
Research use only, not for human use.
Receptor
Immunology/Inflammation related | MMP

Chemical Information

CID 72714324
CAS Number1464910-32-4
PubChem CID72714324
IUPAC Name(2R)-5-(carbamoylamino)-2-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-N-hydroxypentanamide
Molecular FormulaC19H22Br2N4O6S
Molecular Weight594.3
XLogP2.1
Topological Polar Surface Area168
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count11
Heavy Atom Count32
Formal Charge0
Complexity705
SMILES
C1=CC(=CC=C1OCC2=CC(=CC(=C2)Br)Br)S(=O)(=O)N[C@H](CCCNC(=O)N)C(=O)NO
InChI
InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1
InChIKey
QTXVPJOTKLUYMQ-QGZVFWFLSA-N
Chemical Structure
2D Structure
2D structure of CID 72714324
CAS: 1464910-32-4
CID: 72714324
Formula: C19H22Br2N4O6S
MW: 594.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight594.3
XLogP32.1
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count11
Exact Mass593.96063
Monoisotopic Mass591.96268
Topological Polar Surface Area168 Ų
Heavy Atom Count32
Formal Charge0
Complexity705
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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