Hh-Ag1.5

• Description:

  Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quiescent state of non-injured hepatic stem cells and thus rescues liver failure. Hh-Ag1.5 induced differentiation of hiPSCs into skin precursor cells, spinal motor neurons and spinal sensory neurons.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  526.04

• Molecular Formula:

  C28H26ClF2N3OS

• Notes:

  Research use only, not for human use.

• Receptor:

  Hedgehog/Smoothened

• CAS Number:

  612542-14-0