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6-Chloromelatonin

CAT: 1410-M33826-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M33826-01Size:1 Each
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Description
6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for presynaptic melatonin receptor sites in the rabbit retina, inhibiting the calcium-dependent release of [3H]dopamine with higher metabolic stability than melatonin. Chloromelatonin competitively binds to [3H]melatonin at MT2 receptors (pKi=9.77) and may be used to study insomnia and sleep disorders associated with depression.
CAS Number
63762-74-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
266.72
Molecular Formula
C13H15ClN2O2
Notes
Research use only, not for human use.
Receptor
Melatonin Receptor | Dopamine Receptor

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