AACOCF3

CAT: 1410-M33753-01Size: 1 EachDry Ice: NoHazardous: No

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CAT#:1410-M33753-01Size:1 Each

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Description

AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid and a potent, selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2) . By blocking the production of arachidonate and 12-hydroxyeicosatetraenoic acid in calcium ionophore-challenged platelets, AACOCF3 hinders their synthesis. Additionally, AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets, making it promising for cardiovascular disease research.

CAS Number

149301-79-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

356.47

Molecular Formula

C21H31F3O

Notes

Research use only, not for human use.

Receptor

Phospholipase

Alternative Products

Catalog	Name
B6748-25	AACOCF3

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