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Ciglitazone

CAT: 1410-M33630-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M33630-01Size:1 Each
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Description
Ciglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent. Ciglitazone inhibits proliferation and differentiation of th17 cells, decreases insulin levels, vascular endothelial growth factor production and blood pressure, and induces cell cycle arrest in gastric cancer cells. Selegiline induces apoptosis in opossum kidney epithelial cells and activates nuclear translocation of p38 MAPK and apoptosis-inducing factor (AIF) . Ciglitazone exhibits hypoglycaemic activity in animal models of obesity and hyperglycaemia.
CAS Number
74772-77-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
333.45
Molecular Formula
C18H23NO3S
Notes
Research use only, not for human use.
Receptor
PPAR | Apoptosis | p38 MAPK

Alternative Products

CatalogName
B6681-50Ciglitazone
TBI1047-25MGCiglitazone, PPARg agonist

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