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JHU395

CAT: 1410-M32972-01Size: 1 EachDry Ice: NoHazardous: No
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Description
JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON) . It demonstrates delivery of DON to malignant peripheral nerve sheath tumor (MPNST) both in vitro and in vivo, resulting in significant antitumor activity in MPNST. Additionally, JHU395 exhibits plasma stability.
CAS Number
2079938-92-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
447.48
Molecular Formula
C22H29N3O7
Notes
Research use only, not for human use.
Receptor
Apoptosis

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CatalogName
S8892-25mgJHU395

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