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Yangambin

CAT: 1410-M29243-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M29243-02Size:5 mg
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Description
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) ; it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests.
CAS Number
13060-14-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
446.496
Molecular Formula
C24H30O8
Notes
Research use only, not for human use.
Receptor
Calcium Channel

Chemical Information

(+)-Yangambin

Yangambin is a lignan.

CAS Number13060-14-5
PubChem CID443028
IUPAC Name(3S,3aR,6S,6aR)-3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan
Molecular FormulaC24H30O8
Molecular Weight446.5
XLogP2.9
Topological Polar Surface Area73.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Heavy Atom Count32
Formal Charge0
Complexity512
SMILES
COC1=CC(=CC(=C1OC)OC)[C@@H]2[C@H]3CO[C@@H]([C@H]3CO2)C4=CC(=C(C(=C4)OC)OC)OC
InChI
InChI=1S/C24H30O8/c1-25-17-7-13(8-18(26-2)23(17)29-5)21-15-11-32-22(16(15)12-31-21)14-9-19(27-3)24(30-6)20(10-14)28-4/h7-10,15-16,21-22H,11-12H2,1-6H3/t15-,16-,21+,22+/m0/s1
InChIKey
HRLFUIXSXUASEX-RZTYQLBFSA-N
Chemical Structure
2D Structure
2D structure of (+)-Yangambin
CAS: 13060-14-5
CID: 443028
Formula: C24H30O8
MW: 446.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight446.5
XLogP32.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass446.19406791
Monoisotopic Mass446.19406791
Topological Polar Surface Area73.8 Ų
Heavy Atom Count32
Formal Charge0
Complexity512
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-N4267-01Yangambin

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