MRTX1133

• Description :

  MRTX1133 is a potent, selective, noncovalent KRASG12D inhibitor. It has picomolar binding affinity, single-digit nanomolar activity in cellular assays. In addition, it has significant in vivo efficacy in tumor models harboring KRASG12D mutations.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  600.63

• Molecular Formula :

  C33H31F3N6O2

• Notes :

  Research use only, not for human use.

• Receptor :

  ——

• CAS Number :

  2621928-55-8