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MSC2504877

CAT: 1410-M28544-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M28544-02Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
CAS Number
1460286-21-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
282.34
Molecular Formula
C17H18N2O2
Notes
Research use only, not for human use.
Receptor
PTP1B

Chemical Information

3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one
CAS Number1460286-21-8
PubChem CID71765184
IUPAC Name3-[4-(2-hydroxypropan-2-yl)phenyl]-6-methyl-2H-pyrrolo[1,2-a]pyrazin-1-one
Molecular FormulaC17H18N2O2
Molecular Weight282.34
XLogP1.9
Topological Polar Surface Area54.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Heavy Atom Count21
Formal Charge0
Complexity450
SMILES
CC1=CC=C2N1C=C(NC2=O)C3=CC=C(C=C3)C(C)(C)O
InChI
InChI=1S/C17H18N2O2/c1-11-4-9-15-16(20)18-14(10-19(11)15)12-5-7-13(8-6-12)17(2,3)21/h4-10,21H,1-3H3,(H,18,20)
InChIKey
MPXAEYSGFKRDQM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one
CAS: 1460286-21-8
CID: 71765184
Formula: C17H18N2O2
MW: 282.34
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight282.34
XLogP31.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass282.136827821
Monoisotopic Mass282.136827821
Topological Polar Surface Area54.3 Ų
Heavy Atom Count21
Formal Charge0
Complexity450
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA4380-5MSC2504877

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