IDH889

• Description:

  IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μM, and 1.38 μM for IDH1R132H, IDH1R132C, and IDH1wt) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  436.491

• Molecular Formula:

  C23H25FN6O2

• Notes:

  Research use only, not for human use.

• Receptor:

  ——

• CAS Number:

  1429179-07-6