GN44028

CAT: 1410-M26699-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No

1 / 1

CAT#:1410-M26699-02Size:1 mL x 10 mM in DMSO

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

GN44028 is a hypoxia-inducible factor inhibitor of (HIF) -1 (IC50: 14 nM) . GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity.

CAS Number

1421448-26-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

305.337

Molecular Formula

C18H15N3O2

Notes

Research use only, not for human use.

Receptor

Human Endogenous Metabolite

Chemical Information

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine

CAS Number	1421448-26-1
PubChem CID	71625259
IUPAC Name	N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[2,1-d]pyrazol-3-amine
Molecular Formula	C18H15N3O2
Molecular Weight	305.3
XLogP	3.5
Topological Polar Surface Area	59.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Heavy Atom Count	23
Formal Charge	0
Complexity	434

SMILES

C1COC2=C(O1)C=CC(=C2)NC3=NNC4=C3CC5=CC=CC=C54

InChI

InChI=1S/C18H15N3O2/c1-2-4-13-11(3-1)9-14-17(13)20-21-18(14)19-12-5-6-15-16(10-12)23-8-7-22-15/h1-6,10H,7-9H2,(H2,19,20,21)

InChIKey

CGZKSZVSWAAUHE-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1421448-26-1

CID: 71625259

Formula: C18H15N3O2

MW: 305.3

Interactive 3D Structure

Loading 3D structure...

Computed Properties

Property	Value
Molecular Weight	305.3
XLogP3	3.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	305.116426730
Monoisotopic Mass	305.116426730
Topological Polar Surface Area	59.2 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	434
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes