Products for Research Use Only
RegisterLogin

SIRT-IN-1

CAT: 1410-M26447-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M26447-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SIRT-IN-1 is a potent SIRT1/2/3 inhibitor (IC50s of 15, 10, 33 μM, respectively) .
CAS Number
1431411-60-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
389.52
Molecular Formula
C19H27N5O2S
Notes
Research use only, not for human use.
Receptor
KRas G12C

Chemical Information

4-(4-{2-[(2,2-Dimethylpropanoyl)amino]ethyl}piperidin-1-Yl)thieno[3,2-D]pyrimidine-6-Carboxamide
CAS Number1431411-60-7
PubChem CID71304814
IUPAC Name4-[4-[2-(2,2-dimethylpropanoylamino)ethyl]piperidin-1-yl]thieno[3,2-d]pyrimidine-6-carboxamide
Molecular FormulaC19H27N5O2S
Molecular Weight389.5
XLogP2.8
Topological Polar Surface Area129
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count27
Formal Charge0
Complexity545
SMILES
CC(C)(C)C(=O)NCCC1CCN(CC1)C2=NC=NC3=C2SC(=C3)C(=O)N
InChI
InChI=1S/C19H27N5O2S/c1-19(2,3)18(26)21-7-4-12-5-8-24(9-6-12)17-15-13(22-11-23-17)10-14(27-15)16(20)25/h10-12H,4-9H2,1-3H3,(H2,20,25)(H,21,26)
InChIKey
NSPKBHVNVJWICU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(4-{2-[(2,2-Dimethylpropanoyl)amino]ethyl}piperidin-1-Yl)thieno[3,2-D]pyrimidine-6-Carboxamide
CAS: 1431411-60-7
CID: 71304814
Formula: C19H27N5O2S
MW: 389.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight389.5
XLogP32.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass389.18854629
Monoisotopic Mass389.18854629
Topological Polar Surface Area129 Ų
Heavy Atom Count27
Formal Charge0
Complexity545
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M23596-01SIRT-IN-2
M28822-01SIRT1-IN-1
M26448-01Sirt2-IN-1
M13316Sirt2-PROTAC-1
M33124-01SIRT5 inhibitor 1
M12554-01PD-1-IN-1
M36548-01PU.1-IN-1
M28812-01PHD-1-IN-1
M35554-01TGFβ1-IN-1
M37392-011,1-diethoxypentane

Alternative Products

CatalogName
BA4519-1SIRT-IN-1
A20962-500SIRT-IN-1 500mg
A20962-50SIRT-IN-1 50mg
A20962-25SIRT-IN-1 25mg
A20962-100SIRT-IN-1 100mg
A20962-5SIRT-IN-1 5mg
A20962-1SIRT-IN-1 1mg
F52426-0.4MLSIRT-1 Antibody
A20962-10SIRT-IN-1 10mg
BM166497-01Sirt-IN-2

Popular Products