NB-360

• Description:

  NB-360 is a potent and brain-penetrable inhibitor of BACE1 and BACE2 with IC50s of 5, 5, and 6 nM for mouse and human BACE1 and BACE2. NB-360 exhibits excellent selectivity over the related aspartyl proteases pepsin, cathepsin E, and cathepsin D.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  449.41

• Molecular Formula:

  C21H19F4N5O2

• Notes:

  Research use only, not for human use.

• Receptor:

  Lp-PLA2

• CAS Number:

  1262857-73-7