HKI-357

• Description :

  HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM) . HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  574.05

• Molecular Formula :

  C31H29ClFN5O3

• Notes :

  Research use only, not for human use.

• Receptor :

  PEGs

• CAS Number :

  848133-17-5