GNE-1858

• Description :

  GNE-1858 is an ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA) .

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  428.492

• Molecular Formula :

  C21H26F2N8

• Notes :

  Research use only, not for human use.

• Receptor :

  5-HT6

• CAS Number :

  2680616-96-8