F-1

• Description:

  F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  519.02

• Molecular Formula:

  C22H27ClN8O3S

• Notes:

  Research use only, not for human use.

• Receptor:

  ——

• CAS Number:

  2244775-31-1