BSJ-4-116

• Description:

  BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly (adenylation) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  837.38

• Molecular Formula:

  C40H49ClN8O8S

• Notes:

  Research use only, not for human use.

• Receptor:

  CDK12|Cereblon

• CAS Number:

  2519823-34-6