Products for Research Use Only
RegisterLogin

AES-135

CAT: 1410-M24072-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M24072-02Size:1 mL x 10 mM in DMSO
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity.
CAS Number
2361659-61-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
693.66
Molecular Formula
C33H29F6N3O5S
Notes
Research use only, not for human use.
Receptor
HDAC11|HDAC3|HDAC6

Chemical Information

4-((4-tert-butylphenyl)methyl-(2-((4-fluorophenyl)sulfonyl-((2,3,4,5,6-pentafluorophenyl)methyl)amino)acetyl)amino)-N-hydroxybenzamide
CAS Number2361659-61-0
PubChem CID137628685
IUPAC Name4-[(4-tert-butylphenyl)methyl-[2-[(4-fluorophenyl)sulfonyl-[(2,3,4,5,6-pentafluorophenyl)methyl]amino]acetyl]amino]-N-hydroxybenzamide
Molecular FormulaC33H29F6N3O5S
Molecular Weight693.7
XLogP6.2
Topological Polar Surface Area115
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count12
Rotatable Bond Count11
Heavy Atom Count48
Formal Charge0
Complexity1170
SMILES
CC(C)(C)C1=CC=C(C=C1)CN(C2=CC=C(C=C2)C(=O)NO)C(=O)CN(CC3=C(C(=C(C(=C3F)F)F)F)F)S(=O)(=O)C4=CC=C(C=C4)F
InChI
InChI=1S/C33H29F6N3O5S/c1-33(2,3)21-8-4-19(5-9-21)16-42(23-12-6-20(7-13-23)32(44)40-45)26(43)18-41(48(46,47)24-14-10-22(34)11-15-24)17-25-27(35)29(37)31(39)30(38)28(25)36/h4-15,45H,16-18H2,1-3H3,(H,40,44)
InChIKey
LTRKEOBJRDKIHB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-((4-tert-butylphenyl)methyl-(2-((4-fluorophenyl)sulfonyl-((2,3,4,5,6-pentafluorophenyl)methyl)amino)acetyl)amino)-N-hydroxybenzamide
CAS: 2361659-61-0
CID: 137628685
Formula: C33H29F6N3O5S
MW: 693.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight693.7
XLogP36.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count12
Rotatable Bond Count11
Exact Mass693.17321118
Monoisotopic Mass693.17321118
Topological Polar Surface Area115 Ų
Heavy Atom Count48
Formal Charge0
Complexity1170
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M24840-01AES-350
M26630-01BIP-135
M13452-01WY-135
M20281-01135-Trimethoxybenzene
M35544-01DMA-135 hydrochloride
M28868-01VY-3-135
M30354Β-Amyloid Protein Precursor 770 135-155
M24517-01BPH-1358
M33202-01AZ-1355
M28021-01PF-1355

Alternative Products

CatalogName
LUD65961-01AES-135
A19087-25AES-135 25mg
A19087-10AES-135 10mg
A19087-1AES-135 1mg
A19087-100AES-135 100mg
A19087-5AES-135 5mg
A19087-50AES-135 50mg
A19087-10mM-DAES-135 10mM * 1mL in DMSO
pro-169AES
469889AES (AES-1, AES-2, ESP1, GRG, GRG5, TLE5)

Popular Products