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Tanzisertib

CAT: 1410-M22926-01Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M22926-01Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tanzisertib (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Tanzisertib (CC-930) inhibits the formation of phospho-cJun in human PBMC stimulated by phorbol-12-myristate-13-acetate and phytohemeagglutinin (IC50=1 μM) [1] and it blocks the JNK pathway that is activated by pro-fibrotic cytokines in systemic sclerosis.
CAS Number
899805-25-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
448.44
Molecular Formula
C21H23F3N6O2
Notes
Research use only, not for human use.
Receptor
JNK3|JNK2|JNK1

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206052Tanzisertib
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MBS130181-01CC-930(Tanzisertib)
A13564-100CC-930 (Tanzisertib) 100mg
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