N-Nornuciferine hydrochloride

• Description:

  N-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM) .N-Nornuciferine strongly inhibits CYP2D6 activity but shows weak or no inhibition of the other four P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9) . N-Nornuciferine competitively inhibits the CYP2D6-catalyzed dextromethorphan O-demethylation (Ki: 2.34 μM) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  ——

• Molecular Formula:

  ——

• Notes:

  Research use only, not for human use.

• Receptor:

  CYP2D6