BOT-64

CAT: 1410-M22729-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M22729-01Size:1 g
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole compoundBOT-64 inhibits IKKbeta-mediated IkappaBalpha phosphorylation in LPS-activated macrophages, resulting in sequential prevention of downstream events, including proteolytic degradation of IkappaBalpha, DNA binding ability, and transcriptional activity of NF-kappaB.
CAS Number
113760-29-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
273.35
Molecular Formula
C15H15NO2S
Notes
Research use only, not for human use.
Receptor
IKK2

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