SAR-020106

CAT: 1410-M22629-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M22629-01Size:1 g
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Description
SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC (50) of 13.3 nmol/L on the isolated human enzyme. This compound abrogates an etoposide-induced G (2) arrest with an IC (50) of 55 nmol/L in HT29 cells, and significantly enhances the cell killing of gemcitabine and SN38 by 3.0- to 29-fold in several colon tumor lines in vitro and in a p53-dependent fashion.
CAS Number
1184843-57-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
382.85
Molecular Formula
C19H19ClN6O
Notes
Research use only, not for human use.
Receptor
CHK1

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Alternative Products

CatalogName
MBS3846893-01SAR-020106
A22371-5SAR-020106 5mg
A22371-25SAR-020106 25mg
A22371-50SAR-020106 50mg
A22371-1SAR-020106 1mg
A22371-100SAR-020106 100mg
A22371-10SAR-020106 10mg
A22371-10mM-DSAR-020106 10mM * 1mL in DMSO
HY-P4166-01Ac-{Gly (N-me) }-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar
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