9-ING-41

• Description:

  9-ING-41 is a glycogen synthase kinase-3 inhibitor.9-ING-41 (2, 4 μM; 48 hours) decreases neuroblastoma cell viability induces apoptosis[2]. 9-ING-41 (0.1-1 µM) inhibits GSK-3 leading to a decreased expression of the NF-κB target XIAP and significant apoptosis in neuroblastoma cells as shown by PARP cleavage, an apoptosis marker[1]. 9-ING-41 (0.5, 1.0, 1.5, 2.0 μM) inhibits the proliferation rate of all TCL and MCL lines with concentrations as low as 1.0 mM.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  404.35

• Molecular Formula:

  C22H13FN2O5

• Notes:

  Research use only, not for human use.

• Receptor:

  GSK-3β

• CAS Number:

  1034895-42-5