GSK-3β inhibitor 1

• Description:

  GSK-3β inhibitor 1 is an inhibitor of GSK-3β (IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.GSK-3β inhibitor 1 (compound 3a) inhibits GSK-3β with IC50 4.19 nM. In a cell-based assay 3a shows no significant leucocyte toxicity at 10 M and is moderately cytotoxic against A549 cells.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  222.24

• Molecular Formula:

  C14H10N2O

• Notes:

  Research use only, not for human use.

• Receptor:

  GSK-3β

• CAS Number:

  187325-53-7