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Exatecan Mesylate

CAT: 1410-M22421-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M22421-01Size:1 Each
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Description
Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL) .Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.
CAS Number
169869-90-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
531.55
Molecular Formula
C25H26FN3O7S
Notes
Research use only, not for human use.
Receptor
Topo I

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