Exatecan Mesylate

• Description:

  Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL) .Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  531.55

• Molecular Formula:

  C25H26FN3O7S

• Notes:

  Research use only, not for human use.

• Receptor:

  Topo I

• CAS Number:

  169869-90-3