JH-RE-06

CAT: 1410-M22367-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M22367-01Size:1 g
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 also improves chemotherapy.
CAS Number
1361227-90-8
Stability
≄ 2 years
Purity
>98% (HPLC)
Weight
468.72
Molecular Formula
C20H16Cl3N3O4
Notes
Research use only, not for human use.
Receptor
REV1-REV7

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