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L524-0366

CAT: 1410-M22217-07Size: 200 mgDry Ice: NoHazardous: No
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CAT#:1410-M22217-07Size:200 mg
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Description
L524-0366 is a TWEAK-Fn14 signaling cascade inhibitor.L524-0366 mitigated maladaptive remodeling with TAC. TWEAK induced secretion of the pro-inflammatory chemokine, monocyte chemoattractant protein 1 from WT but not Fn14-/- fibroblasts in vitro, in part through activation of non-canonical NF-κB signaling.
CAS Number
951612-19-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
308.79
Molecular Formula
C13H13ClN4OS
Notes
Research use only, not for human use.
Receptor
Fn14

Chemical Information

4-[1-(3-Chlorophenyl)-1H-1,2,3-triazole-4-carbonyl]thiomorpholine
CAS Number951612-19-4
PubChem CID20973801
IUPAC Name[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholin-4-ylmethanone
Molecular FormulaC13H13ClN4OS
Molecular Weight308.79
XLogP2.2
Topological Polar Surface Area76.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity353
SMILES
C1CSCCN1C(=O)C2=CN(N=N2)C3=CC(=CC=C3)Cl
InChI
InChI=1S/C13H13ClN4OS/c14-10-2-1-3-11(8-10)18-9-12(15-16-18)13(19)17-4-6-20-7-5-17/h1-3,8-9H,4-7H2
InChIKey
ZOBDTKWDYMRKPF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-[1-(3-Chlorophenyl)-1H-1,2,3-triazole-4-carbonyl]thiomorpholine
CAS: 951612-19-4
CID: 20973801
Formula: C13H13ClN4OS
MW: 308.79
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight308.79
XLogP32.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass308.0498599
Monoisotopic Mass308.0498599
Topological Polar Surface Area76.3 Ų
Heavy Atom Count20
Formal Charge0
Complexity353
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
bs-82311C-01L524-0366
TBI1536-25MGL524-0366, Fn14 antagonist
GTR19216104-01ALC-0366
MBS1341848-01Recombinant Acanthamoeba polyphaga mimivirus Uncharacterized protein L524 (MIMI_L524)
ABP-Q-0366Human B2M Matched Antibody Pair Set [ABP-Q-0366]

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