Tibolone

CAT: 1410-M18813-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:1410-M18813-01Size:25 mg

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Description

Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the treatment of osteoporosis.

CAS Number

5630-53-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

312.45

Molecular Formula

C21H28O2

Notes

Research use only, not for human use.

Receptor

Chemical Information

Tibolone

Tibolone is estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis. It has a role as a bone density conservation agent and a hormone agonist. It is a 17beta-hydroxy steroid and a terminal acetylenic compound.

CAS Number	5630-53-5
PubChem CID	444008
IUPAC Name	(7R,8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-7,13-dimethyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Molecular Formula	C21H28O2
Molecular Weight	312.4
XLogP	2.4
Topological Polar Surface Area	37.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Heavy Atom Count	23
Formal Charge	0
Complexity	635

SMILES

C[C@@H]1CC2=C(CCC(=O)C2)[C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(C#C)O

InChI

InChI=1S/C21H28O2/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3/h1,13,17-19,23H,5-12H2,2-3H3/t13-,17-,18+,19-,20+,21+/m1/s1

InChIKey

WZDGZWOAQTVYBX-XOINTXKNSA-N

Chemical Structure

2D Structure

CAS: 5630-53-5

CID: 444008

Formula: C21H28O2

MW: 312.4

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	312.4
XLogP3	2.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	312.208930132
Monoisotopic Mass	312.208930132
Topological Polar Surface Area	37.3 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	635
Isotope Atom Count	0
Defined Atom Stereocenter Count	6
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
FT35065-01	Tibolone
TRC-T437495-10MG	7Beta-Tibolone
CS-O-03644	Tibolone-d5
290169-01	∆4-Tibolone
HY-123047R-01	Tibolone (Standard)
CS-O-44754	Tibolone-d6
439911-01	7β-Tibolone
RM-T090211-01	Tibolone D5
CS-O-06132	Delta-4-Tibolone
CS-T-60286	Tibolone Impurity B

Tibolone

Chemical Information

Alternative Products

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