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PIK75

CAT: 1410-M18485-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M18485-02Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PIK-75 Hydrochloride is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
CAS Number
372196-67-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
452.28
Molecular Formula
C16H14BrN5O4S
Notes
Research use only, not for human use.
Receptor
DNA-PK| p110α| p110β| p110γ| p110δ

Chemical Information

Pik-75

N-[(6-bromo-3-imidazo[1,2-a]pyridinyl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide is a sulfonamide.

CAS Number372196-67-3
PubChem CID10275789
IUPAC NameN-[(E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide
Molecular FormulaC16H14BrN5O4S
Molecular Weight452.3
XLogP3.8
Topological Polar Surface Area121
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Heavy Atom Count27
Formal Charge0
Complexity679
SMILES
CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)/N=C/C2=CN=C3N2C=C(C=C3)Br
InChI
InChI=1S/C16H14BrN5O4S/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16/h3-10H,1-2H3/b19-9+
InChIKey
QTHCAAFKVUWAFI-DJKKODMXSA-N
Chemical Structure
2D Structure
2D structure of Pik-75
CAS: 372196-67-3
CID: 10275789
Formula: C16H14BrN5O4S
MW: 452.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight452.3
XLogP33.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass450.99499
Monoisotopic Mass450.99499
Topological Polar Surface Area121 Ų
Heavy Atom Count27
Formal Charge0
Complexity679
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B1668-25PIK75

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