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NU1025

CAT: 1410-M17652-04Size: 10 mgDry Ice: NoHazardous: No
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CAT#:1410-M17652-04Size:10 mg
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Description
NU1025 is a potent PARP inhibitor with IC50 of 400 nM.
CAS Number
90417-38-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
176.17
Molecular Formula
C9H8N2O2
Notes
Research use only, not for human use.
Receptor
PARP

Chemical Information

8-Hydroxy-2-methyl-4(3H)-quinazolinone

NU 1025 is a member of the class of quinazolines that is quinazolin-4(1H)-one substituted by a hydroxy group at position 8 and a methyl group at position 2. It has been shown to exhibit inhibitory activity against poly(ADP-ribose) polymerase. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. It is a member of phenols and a member of quinazolines.

CAS Number90417-38-2
PubChem CID135398517
IUPAC Name8-hydroxy-2-methyl-3H-quinazolin-4-one
Molecular FormulaC9H8N2O2
Molecular Weight176.17
XLogP0.3
Topological Polar Surface Area61.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Heavy Atom Count13
Formal Charge0
Complexity262
SMILES
CC1=NC2=C(C=CC=C2O)C(=O)N1
InChI
InChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13)
InChIKey
YJDAOHJWLUNFLX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 8-Hydroxy-2-methyl-4(3H)-quinazolinone
CAS: 90417-38-2
CID: 135398517
Formula: C9H8N2O2
MW: 176.17
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight176.17
XLogP30.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass176.058577502
Monoisotopic Mass176.058577502
Topological Polar Surface Area61.7 Ų
Heavy Atom Count13
Formal Charge0
Complexity262
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS3607646-01NU1025

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