TAK-285

• Description:

  TAK-285 is a novel dual HER2 and EGFR (HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  547.96

• Molecular Formula:

  C26H25ClF3N5O3

• Notes:

  Research use only, not for human use.

• Receptor:

  Aurora B| EGFR/HER1| HER2| HER4| MEK1

• CAS Number:

  871026-44-7