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SB415286

CAT: 1410-M17460-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M17460-01Size:5 mg
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Description
SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.
CAS Number
264218-23-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
359.72
Molecular Formula
C16H10ClN3O5
Notes
Research use only, not for human use.
Receptor
GSK-3α , GSK-3β

Chemical Information

SB 415286

SB 415286 is a member of the class of maleimides carrying 3-chloro-4-hydroxyphenylamino and 2-nitrophenyl substituents at positions 3 and 4 respectively. It has a role as an antioxidant, a neuroprotective agent, an apoptosis inducer and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a member of phenols, a C-nitro compound, a substituted aniline, a secondary amino compound, a member of maleimides and a member of monochlorobenzenes.

CAS Number264218-23-7
PubChem CID4210951
IUPAC Name3-(3-chloro-4-hydroxyanilino)-4-(2-nitrophenyl)pyrrole-2,5-dione
Molecular FormulaC16H10ClN3O5
Molecular Weight359.72
XLogP2.8
Topological Polar Surface Area124
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count25
Formal Charge0
Complexity617
SMILES
C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl)[N+](=O)[O-]
InChI
InChI=1S/C16H10ClN3O5/c17-10-7-8(5-6-12(10)21)18-14-13(15(22)19-16(14)23)9-3-1-2-4-11(9)20(24)25/h1-7,21H,(H2,18,19,22,23)
InChIKey
PQCXVIPXISBFPN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of SB 415286
CAS: 264218-23-7
CID: 4210951
Formula: C16H10ClN3O5
MW: 359.72
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight359.72
XLogP32.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass359.0308981
Monoisotopic Mass359.0308981
Topological Polar Surface Area124 Ų
Heavy Atom Count25
Formal Charge0
Complexity617
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
S2729-50mgSB415286

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