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AM281

CAT: 1410-M17418-07Size: 500 mgDry Ice: NoHazardous: No
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CAT#:1410-M17418-07Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.
CAS Number
202463-68-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
557.21
Molecular Formula
C21H19Cl2IN4O2
Notes
Research use only, not for human use.
Receptor
CB

Chemical Information

AM 281

1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(4-morpholinyl)-3-pyrazolecarboxamide is a member of pyrazoles and a ring assembly.

CAS Number202463-68-1
PubChem CID4302962
IUPAC Name1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholin-4-ylpyrazole-3-carboxamide
Molecular FormulaC21H19Cl2IN4O2
Molecular Weight557.2
XLogP5.3
Topological Polar Surface Area59.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count30
Formal Charge0
Complexity589
SMILES
CC1=C(N(N=C1C(=O)NN2CCOCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)I
InChI
InChI=1S/C21H19Cl2IN4O2/c1-13-19(21(29)26-27-8-10-30-11-9-27)25-28(18-7-4-15(22)12-17(18)23)20(13)14-2-5-16(24)6-3-14/h2-7,12H,8-11H2,1H3,(H,26,29)
InChIKey
AJFFBPZYXRNAIC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of AM 281
CAS: 202463-68-1
CID: 4302962
Formula: C21H19Cl2IN4O2
MW: 557.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight557.2
XLogP35.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass555.99298
Monoisotopic Mass555.99298
Topological Polar Surface Area59.4 Ų
Heavy Atom Count30
Formal Charge0
Complexity589
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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