WZ3146

• Description :

  WZ3146 is a mutant-selective irreversible inhibitor of EGFR (L858R) and EGFR (E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I) .

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  464.95

• Molecular Formula :

  C24H25ClN6O2

• Notes :

  Research use only, not for human use.

• Receptor :

  EGFR (E746_A750) | EGFR (E746_A750/T790M) | EGFR (L858R) | EGFR (L858R/T790M)

• CAS Number :

  1214265-56-1