Products for Research Use Only
RegisterLogin

Merestinib

CAT: 1410-M17192-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M17192-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LY2801653 is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity.
CAS Number
1206799-15-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
552.54
Molecular Formula
C30H22F2N6O3
Notes
Research use only, not for human use.
Receptor
Met

Chemical Information

Merestinib

Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.

CAS Number1206799-15-6
PubChem CID44603533
IUPAC NameN-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide
Molecular FormulaC30H22F2N6O3
Molecular Weight552.5
XLogP4.7
Topological Polar Surface Area105
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count41
Formal Charge0
Complexity1050
SMILES
CC1=CC=C(C(=O)N1C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C=C5C(=C4)C=NN5C)C6=CNN=C6)F
InChI
InChI=1S/C30H22F2N6O3/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-15-19/h3-16H,1-2H3,(H,33,34)(H,36,39)
InChIKey
QHADVLVFMKEIIP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Merestinib
CAS: 1206799-15-6
CID: 44603533
Formula: C30H22F2N6O3
MW: 552.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight552.5
XLogP34.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass552.17214491
Monoisotopic Mass552.17214491
Topological Polar Surface Area105 Ų
Heavy Atom Count41
Formal Charge0
Complexity1050
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T3455-01Merestinib
MBS385090-01LY2801653 (Merestinib)
S7014-5mgMerestinib (LY2801653)
E7462Merestinib dihydrochloride
A12557-1LY2801653 (Merestinib) 1mg
A12557-500LY2801653 (Merestinib) 500mg

Popular Products