AT-7519 hydrochloride

• Description:

  A potent CDK2 inhibitor with IC50 of 47 nM; also inhibits CDK1/4/5 with IC50 of 190/67/18 nM and shows selectivity over some kinases (Aurora A, IR kinase, MEK, PDK1, c-Abl, IC50>10 uM) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  418.7054

• Molecular Formula:

  C16H18Cl3N5O2

• Notes:

  Research use only, not for human use.

• Receptor:

  CDK2/CyclinA|CDK4/CyclinD1|CDK5/p35|CDK9/CyclinT|GSK-3β

• CAS Number:

  902135-91-5