Products for Research Use Only
RegisterLogin

BFH-772

CAT: 1410-M16425-04Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M16425-04Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent, selective and orally active VEGFR2 tyrosine kinase inhibitor with IC50 of 3 nM.
CAS Number
890128-81-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
439.3867
Molecular Formula
C23H16F3N3O3
Notes
Research use only, not for human use.
Receptor
VEGFR2

Chemical Information

Bfh-772

BFH772 is under investigation in clinical trial NCT01449591 (Safety, Tolerability and Efficacy of BFH772 in Rosacea Patients).

CAS Number890128-81-1
PubChem CID24756034
IUPAC Name6-[6-(hydroxymethyl)pyrimidin-4-yl]oxy-N-[3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide
Molecular FormulaC23H16F3N3O3
Molecular Weight439.4
XLogP4.2
Topological Polar Surface Area84.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Heavy Atom Count32
Formal Charge0
Complexity635
SMILES
C1=CC(=CC(=C1)NC(=O)C2=CC=CC3=C2C=CC(=C3)OC4=NC=NC(=C4)CO)C(F)(F)F
InChI
InChI=1S/C23H16F3N3O3/c24-23(25,26)15-4-2-5-16(10-15)29-22(31)20-6-1-3-14-9-18(7-8-19(14)20)32-21-11-17(12-30)27-13-28-21/h1-11,13,30H,12H2,(H,29,31)
InChIKey
JNLSTLQFDDAULK-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Bfh-772
CAS: 890128-81-1
CID: 24756034
Formula: C23H16F3N3O3
MW: 439.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight439.4
XLogP34.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass439.11437587
Monoisotopic Mass439.11437587
Topological Polar Surface Area84.3 Ų
Heavy Atom Count32
Formal Charge0
Complexity635
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS131563BFH-772
MBS5777486L-772,405
GTR19258018-01ONO-TR-772
HY-W999699CRBN ligand-772
MBS474145-01Semaphorin-6A (a.a. 772-787)
496842ZNF772 (Zinc Finger Protein 772)
APR17469GPolyclonal MPRIP / RIP3 Antibody (aa723-772)
PH50899I0TLK2 Protein, Human, Recombinant (aa 397-772)
NBP1-84113-25ulRabbit Polyclonal Zinc finger protein 772 Antibody
H00400720-B01PMouse Polyclonal Zinc finger protein 772 Antibody

Popular Products