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AZD2932

CAT: 1410-M16404-04Size: 25 mgDry Ice: NoHazardous: No
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CAT#:1410-M16404-04Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD2932 is a new series of quinazoline ether inhibitor which potently inhibits VEGFR-2 and PDGFR with IC50s of 4 nM/8 nM/ 7 nM for PDGFRβ/VEGFR-2/Flt-3.
CAS Number
883986-34-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
447.49
Molecular Formula
C24H25N5O4
Notes
Research use only, not for human use.
Receptor
C-Kit| FLT3| PDGFRβ| VEGFR2

Chemical Information

2-(4-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide

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CAS Number883986-34-3
PubChem CID11517980
IUPAC Name2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-N-(1-propan-2-ylpyrazol-4-yl)acetamide
Molecular FormulaC24H25N5O4
Molecular Weight447.5
XLogP3.1
Topological Polar Surface Area100
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Heavy Atom Count33
Formal Charge0
Complexity630
SMILES
CC(C)N1C=C(C=N1)NC(=O)CC2=CC=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC
InChI
InChI=1S/C24H25N5O4/c1-15(2)29-13-17(12-27-29)28-23(30)9-16-5-7-18(8-6-16)33-24-19-10-21(31-3)22(32-4)11-20(19)25-14-26-24/h5-8,10-15H,9H2,1-4H3,(H,28,30)
InChIKey
TWYCZJMOEMMCGC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(4-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide
CAS: 883986-34-3
CID: 11517980
Formula: C24H25N5O4
MW: 447.5
Interactive 3D Structure
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Computed Properties
PropertyValue
Molecular Weight447.5
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Exact Mass447.19065430
Monoisotopic Mass447.19065430
Topological Polar Surface Area100 Ų
Heavy Atom Count33
Formal Charge0
Complexity630
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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