Products for Research Use Only
RegisterLogin

RO4987655

CAT: 1410-M16357-05Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M16357-05Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A potent and highly selective small-molecule MEK inhibitor with IC50 of 5.2 nM.
CAS Number
874101-00-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
565.2816
Molecular Formula
C20H19F3IN3O5
Notes
Research use only, not for human use.
Receptor
MEK1|MEK2

Chemical Information

Ro-4987655

RO4987655 has been used in trials studying the treatment of Neoplasms.

CAS Number874101-00-5
PubChem CID11548630
IUPAC Name3,4-difluoro-2-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)-5-[(3-oxooxazinan-2-yl)methyl]benzamide
Molecular FormulaC20H19F3IN3O5
Molecular Weight565.3
XLogP3
Topological Polar Surface Area100
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count8
Heavy Atom Count32
Formal Charge0
Complexity652
SMILES
C1CC(=O)N(OC1)CC2=CC(=C(C(=C2F)F)NC3=C(C=C(C=C3)I)F)C(=O)NOCCO
InChI
InChI=1S/C20H19F3IN3O5/c21-14-9-12(24)3-4-15(14)25-19-13(20(30)26-31-7-5-28)8-11(17(22)18(19)23)10-27-16(29)2-1-6-32-27/h3-4,8-9,25,28H,1-2,5-7,10H2,(H,26,30)
InChIKey
FIMYFEGKMOCQKT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Ro-4987655
CAS: 874101-00-5
CID: 11548630
Formula: C20H19F3IN3O5
MW: 565.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight565.3
XLogP33
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count8
Exact Mass565.03215
Monoisotopic Mass565.03215
Topological Polar Surface Area100 Ų
Heavy Atom Count32
Formal Charge0
Complexity652
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B3261-10RO4987655
A13272-100RO4987655 100mg
A13272-5RO4987655 5mg
A13272-1RO4987655 1mg
A13272-50RO4987655 50mg
A13272-10RO4987655 10mg
HY-14719RRO4987655 (Standard)
A13272-25RO4987655 25mg
A13272-2RO4987655 2mg
A13272-10mM-DRO4987655 10mM * 1mL in DMSO

Popular Products