Palbociclib hydrochloride

• Description:

  A potent and selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM; no inhibition for CDK2A (IC50>5 uM) ; inhibits MDA-MB453 cells with IC50 of 0.16 uM.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  483.9937

• Molecular Formula:

  C24H30ClN7O2

• Notes:

  Research use only, not for human use.

• Receptor:

  CDK2/CyclinA|CDK2/CyclinE2|CDK4/CyclinD1|CDK4/CyclinD3|CDK6/CyclinD2

• CAS Number:

  827022-32-2