PHA-848125

CAT: 1410-M16004-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M16004-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, selective, brain penetrant and orally available dual CDK and TRK inhibitor with IC50 of 45 and 53 nM for CDK2/cyclin A and TrkA, respectively; shows cross-reactivity with other CDKs (CDK1/4/5/7), TrkB/C, Kit, Abl and PDGFR (IC50s<1 uM) .
CAS Number
802539-81-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
460.5746
Molecular Formula
C25H32N8O
Notes
Research use only, not for human use.
Receptor
CDK2/CyclinA| CDK4/CyclinD1| CDK5/p35| CDK7/CyclinH| TrkA

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