SMER-28

• Description:

  A small-molecule enhancer/inducer of Autophagy; decreases the levels of Aβ peptide (EC50=10 uM) and APP-CTF (EC50 of 20 uM) in a γ-secretase-independent manner in primary neuronal cultures, Atg5, Beclin1 and Ulk1 are shown to be involved in the degradation of Aβ and APP-CTF.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  264.1212

• Molecular Formula:

  C11H10BrN3

• Notes:

  Research use only, not for human use.

• Receptor:

  Autophagy

• CAS Number:

  307538-42-7