SMER-28

• Description :

  A small-molecule enhancer/inducer of Autophagy; decreases the levels of Aβ peptide (EC50=10 uM) and APP-CTF (EC50 of 20 uM) in a γ-secretase-independent manner in primary neuronal cultures, Atg5, Beclin1 and Ulk1 are shown to be involved in the degradation of Aβ and APP-CTF.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  264.1212

• Molecular Formula :

  C11H10BrN3

• Notes :

  Research use only, not for human use.

• Receptor :

  Autophagy

• CAS Number :

  307538-42-7