BAY-1895344

• Description:

  BAY-1895344 is a potent, selective, orally active ATR inhibitor with low-nanomolar potency; potently inhibits the proliferation of a broad spectrum of human tumor cell lines with mean IC50 of 78 nM; inhibits hydroxyurea-induced H2AX phosphorylation, exhibits strong in vivo anti-tumor efficacy in monotherapy in a variety of xenograft models.Blood Cancer, Phase 1 Clinical

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  375.436

• Molecular Formula:

  C20H21N7O

• Notes:

  Research use only, not for human use.

• Receptor:

  ATM/ATR

• CAS Number:

  1876467-74-1