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IC261

CAT: 1410-M12882-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:1410-M12882-03Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IC261 (IC-261, SU-5607) is a potent, specific, ATP-competitive CK1delta/epsilon (CK1δ/CK1ε) with IC50 of 1 uM, does not block the activity of α, β and γ isoforms.
CAS Number
186611-52-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
311.3319
Molecular Formula
C18H17NO4
Notes
Research use only, not for human use.
Receptor
CDK5|CK1

Chemical Information

IC261

a caseine kinase-1 inhibitor; structure in first source

CAS Number186611-52-9
PubChem CID5288600
IUPAC Name(3E)-3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one
Molecular FormulaC18H17NO4
Molecular Weight311.3
XLogP2.8
Topological Polar Surface Area56.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity450
SMILES
COC1=CC(=C(C(=C1)OC)/C=C/2\C3=CC=CC=C3NC2=O)OC
InChI
InChI=1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20)/b13-10+
InChIKey
JBJYTZXCZDNOJW-JLHYYAGUSA-N
Chemical Structure
2D Structure
2D structure of IC261
CAS: 186611-52-9
CID: 5288600
Formula: C18H17NO4
MW: 311.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight311.3
XLogP32.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass311.11575802
Monoisotopic Mass311.11575802
Topological Polar Surface Area56.8 Ų
Heavy Atom Count23
Formal Charge0
Complexity450
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B6108-10IC261

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