Avapritinib

• Description:

  Avapritinib (BLU-285) is a potent and highly selective inhibitor of mutant KIT and PDGFRα with IC50 of 0.6, 0.27 and 0.24 nM for KIT del557-558, KIT D816V and PDGFRA D842V, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  498.57

• Molecular Formula:

  C26H27FN10

• Notes:

  Research use only, not for human use.

• Receptor:

  KITD816V|PDGFRαD842V

• CAS Number:

  1703793-34-3