Avapritinib

• Description :

  Avapritinib (BLU-285) is a potent and highly selective inhibitor of mutant KIT and PDGFRα with IC50 of 0.6, 0.27 and 0.24 nM for KIT del557-558, KIT D816V and PDGFRA D842V, respectively.

• CAS Number :

  1703793-34-3

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  498.57

• Molecular Formula :

  C26H27FN10

• Notes :

  Research use only, not for human use.

• Receptor :

  KITD816V|PDGFRαD842V