Products for Research Use Only

CCT251545

CAT: 1410-M12536-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M12536-01Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCT251545 is a potent, orally bioavailable inhibitor of Wnt signaling with IC50 of 5 nM, also is a potent and selective chemical probe for CDK8 and CDK19 with >100-fold selectivity over 291 other kinases; potently inhibits reporter-based readouts of basal WNT pathway activity in LS174T and SW480 cells in the absence of WNT ligand with IC50 of 23 and 190 nM, respectively.
CAS Number
1661839-45-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
421.9225
Molecular Formula
C23H24ClN5O
Notes
Research use only, not for human use.
Receptor
CDK