Products for Research Use Only
RegisterLogin

SAR405

CAT: 1410-M12127-01Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M12127-01Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SAR405 is a highly potent and selective PI3K class III isoform Vps34 inhibitor with IC50 of 1.2 nM.
CAS Number
1523406-39-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
443.8506
Molecular Formula
C19H21ClF3N5O2
Notes
Research use only, not for human use.
Receptor
PI3K

Chemical Information

Sar405

a Vps34 inhibitor with antineoplastic activity; structure in first source

CAS Number1523406-39-4
PubChem CID72709209
IUPAC Name(8S)-9-[(5-chloro-3-pyridinyl)methyl]-2-[(3R)-3-methylmorpholin-4-yl]-8-(trifluoromethyl)-7,8-dihydro-6H-pyrimido[1,2-a]pyrimidin-4-one
Molecular FormulaC19H21ClF3N5O2
Molecular Weight443.8
XLogP2.2
Topological Polar Surface Area61.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Heavy Atom Count30
Formal Charge0
Complexity731
SMILES
C[C@@H]1COCCN1C2=CC(=O)N3CC[C@H](N(C3=N2)CC4=CC(=CN=C4)Cl)C(F)(F)F
InChI
InChI=1S/C19H21ClF3N5O2/c1-12-11-30-5-4-26(12)16-7-17(29)27-3-2-15(19(21,22)23)28(18(27)25-16)10-13-6-14(20)9-24-8-13/h6-9,12,15H,2-5,10-11H2,1H3/t12-,15+/m1/s1
InChIKey
SPDQRCUBFSRAFI-DOMZBBRYSA-N
Chemical Structure
2D Structure
2D structure of Sar405
CAS: 1523406-39-4
CID: 72709209
Formula: C19H21ClF3N5O2
MW: 443.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight443.8
XLogP32.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass443.1335871
Monoisotopic Mass443.1335871
Topological Polar Surface Area61.3 Ų
Heavy Atom Count30
Formal Charge0
Complexity731
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M40128(D-Arg2, Sar4) -Dermorphin (1-4)

Alternative Products

CatalogName
MBS3602127-01SAR405
A21345-2SAR405 2mg
A21345-1SAR405 1mg
A21345-50SAR405 50mg
A21345-25SAR405 25mg
A21345-5SAR405 5mg
A21345-10SAR405 10mg
HY-12481A-01SAR405 R enantiomer

Popular Products