UCT943

CAT: 1410-M11936-02Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:1410-M11936-02Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

UCT943 (UCT-943) is a potent, selective, next generation Plasmodium falciparum PI4K inhibitor with IC50 of 23 nM.

CAS Number

1450666-80-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

427.431

Molecular Formula

C22H20F3N5O

Notes

Research use only, not for human use.

Receptor

PI4K

Chemical Information

[4-[5-Amino-6-[4-(trifluoromethyl)phenyl]pyrazin-2-yl]phenyl]-piperazin-1-ylmethanone

CAS Number	1450666-80-4
PubChem CID	71711915
IUPAC Name	[4-[5-amino-6-[4-(trifluoromethyl)phenyl]pyrazin-2-yl]phenyl]-piperazin-1-ylmethanone
Molecular Formula	C22H20F3N5O
Molecular Weight	427.4
XLogP	2.4
Topological Polar Surface Area	84.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	3
Heavy Atom Count	31
Formal Charge	0
Complexity	596

SMILES

C1CN(CCN1)C(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C4=CC=C(C=C4)C(F)(F)F)N

InChI

InChI=1S/C22H20F3N5O/c23-22(24,25)17-7-5-15(6-8-17)19-20(26)28-13-18(29-19)14-1-3-16(4-2-14)21(31)30-11-9-27-10-12-30/h1-8,13,27H,9-12H2,(H2,26,28)

InChIKey

GGOFGCMPKAWHEZ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1450666-80-4

CID: 71711915

Formula: C22H20F3N5O

MW: 427.4

Interactive 3D Structure

Loading 3D structure...

Computed Properties

Property	Value
Molecular Weight	427.4
XLogP3	2.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	3
Exact Mass	427.16199476
Monoisotopic Mass	427.16199476
Topological Polar Surface Area	84.1 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	596
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes