RO 2443

• Description:

  RO 2443 is a potent, dual MDM2/MDMX antagonist that inhibits both MDM2 (IC50=33 nM) and MDMX (IC50=41 nM) binding to p53.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  401.798

• Molecular Formula:

  C20H14ClF2N3O2

• Notes:

  Research use only, not for human use.

• Receptor:

  MDM2-p53

• CAS Number:

  1416663-79-0