Dabrafenib

• Description:

  Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM in cell-free assays, with 4- and 6-fold less potency against B-Raf (wt) and c-Raf, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  519.56

• Molecular Formula:

  C23H20F3N5O2S2

• Notes:

  Research use only, not for human use.

• Receptor:

  B-Raf| B-Raf (V600E) | C-Raf

• CAS Number:

  1195765-45-7